Vanilla Fudge were inducted into the Long Island Music Hall of Fame by Felix Cavaliere for their contribution to music history. In the summer of 2006, the original Vanilla Fudge reunited to tour with The Doors of the 21st Century; it culminated in a VH-1 special, “Decades of Rock.”

In the summer of 2007, HBO's final episode of The Sopranos featured "You Keep Me Hangin' On" as a theme for their cliffhanger. The band also went back into the studio to record Out Through the In Door, a Led Zeppelin cover album released in 2007 only in Europe. Also, the band performed "You Keep Me Hangin' On" for the PBS fundraising program My Music: My Generation – The '60s for the March 2008 pledge drive.

In March 2008, the original lineup of Vanilla Fudge embarked on a tour of the United States. In the summer of that year, Bogert and Appice left to concentrate on Cactus, which they had reformed in 2006. Stein and Martell continued on in 2008 and 2009 as Mark Stein and Vince Martell of Vanilla Fudge with a tour that was called "Let's Pray For Peace," with Jimmyjack Tamburo on drums and Pete Bremy returning on bass. Out Through the In Door was released in the US in 2008. Stein and Martell also performed shows during this period with Steve Argy and Jimmyjack Tamburo again as the rhythm section.

In 2009, Tim Bogert announced his retirement from touring and was replaced later by Pete Bremy. In early 2011, Vanilla Fudge embarked on what was announced as their farewell tour. The lineup for the tour was: Carmine Appice, Mark Stein, Vince Martell, and Pete Bremy.